The track will be clockwise. Besides the turn numbers, it's very rare for a street/road course to go clockwise - no current Indycar course goes counter-clockwise.
The reason I say cars will be able to stretch their legs a bit is there's two decent-sized straights for a street course - D Street's about 1/3rd of a mile, while Congress Street is over half a mile. You should see cars hitting 5th in the first and 6th in the second, probably going about 170-175 into Turn 4. That's pretty good for an Indycar in road course trim.
The 500 is this afternoon and I'm watching old ones on YouTube. Currently watching 1992, where Michael dominated the field (which included: Mario, AJ Foyt, Al Unser, Little Al, Emerson Fittipaldi, Bobby Rahal, Rick Mears, Gordon Johncock, Danny Sullivan and rookies Jimmy Vasser and Paul Tracy - what a field!). How did it never work for that guy?