Yeah, that combination isn't within 100 miles of a mixup. He was just taking it all, in whatever combination. He's definitely a full blown addict and without a serious desire to stop, he's got no chance.
His career isn't over, in that he could play on the Senior Tour down the road if he wants to hack it around. He'll never be in the Top 25 of the WGR again.
But you would be surprised at how a body can snap back when you're taken the right actions to get your life together. If Tiger does that, he could at least compete again, even if the days of dominating are way over.