The Vikings have a good O-line but without AP they're not great on skill position players -- Patterson is it, as he's explosive. They'll have to run a balanced attack and need to control the line of scrimmage in order to do that. I don't think they can be one-dimensional due to lack of skill players and a need to keep the Pats from focusing on any one dimension. The line of scrimmage is obviously key for any game, but more so here. If it can allow them to generate a decent running game and short passing attack, then they'll be in the game. The Pats have to hope that Revis earns his keep by holding Patterson down (as a receiver) and that the rest of the team can do a good enough job stuffing the run/generating a pass rush such that Vikings can only win if Cassell/Rudolph or the 2 back-up running backs work wonders. Doubt they have the skill to do that absent big holes/lots of time in the pocket.
In other words, this is a big test for Wilfork, Siliga, Easley, Jones, Nink and whoever else rotates in. If they do their job, then the Pats should be fine.